Journal Articles


B.A. Zambrano, N. McLean, X. Zhao, J.L. Tan, L. Zhong, C.A. Figueroa, L.C. Lee, S. Baek.Image-based computational assessment of vascular wall mechanics and hemodynamics in pulmonary arterial hypertension patients”. Journal of Biomechanics. Vol 68, pp. 84–92 pdf_icon_20w.

M.S. Vieira, M. Henningsson, N. Dedieu, R. Botnar, A. Bell, S. Mathur, K. Pushparajah, C.A. Figueroa, T. Hussain, G.F. Greil. “Improved Coronary Magnetic Resonance Angiography using Gadobenate Dimeglumine in Pediatric Congenital Heart Disease”. Magnetic Resonance Imaging. DOI: 10.1016/j.mri.2017.12.023pdf_icon_20w.

T.M.J. van Bakel, C.J. Arthurs, J.A. Herwaarden, F.L. Moll, K.A. Eagle, H.J. Patel, S. Trimarchi, C.A. Figueroa. “Hemodynamic Performance of Different Endograft Designs for Zone 0 Aortic Arch Repair: A Computational Study”. European Journal of Cardio-Thoracic Surgery. DOI: 10.1093/ejcts/ezy068 pdf_icon_20w.

T.M.J. van Bakel, C. Alberto Figueroa, J.A. Herwaarden, S. Trimarchi. “Challenges of Thoracic Endovascular Aortic Repair for Type B Aortic Dissection”. Journal of Endovascular Therapy. Vol 25(5), pp. 578 – 580pdf_icon_20w.

J. Edlin, R. Bilkhu, P. Youssefi, C.A. Figueroa, R. Morgan, J. Nowell, M. Jahangiri. “Hemodynamic Assessment of Bicuspid Valve Aortopathy: A Review of Current Literature”. European Journal of Cardiothoracic Surgery. DOI: 10.1093/ejcts/ezy312pdf_icon_20w.

M.S. Vieira, C.J. Arthurs, T. Hussain, R. Razavi, C.A. Figueroa. “Patient-specific modeling of right coronary circulation vulnerability post-liver transplant in Alagille’s syndrome”. PLOS ONE. DOI: 10.1371/journal.pone.0205829pdf_icon_20w.



A. van Engelen, M.S. Vieira, I. Rafiq, M. Cecelja, T. Scheider, H. de Bliek, C.A. Figueroa, T. Hussain, R. Botnar, J. Alastruey. “Aortic Length Measurements for Pulse Wave Velocity Calculation: Manual 2D vs Semi-automated 3D centerline extraction”. Journal of Cardiovascular Magnetic Resonance. DOI: 10.1186/s12968-017-0341-y pdf_icon_20w.

F. Cuomo, S. Roccabianca, N. Xiao, D. Dillon-Murphy, J.D. Humphrey, C.A. Figueroa. “Effects of Age-Associated Regional Changes in Central Artery Stiffness on Human Systemic Hemodynamics Revealed by Computational Modeling”. PLOS ONE. DOI: 10.1371/journal.pone.0173177 pdf_icon_20w.

C.J. Arthurs, P. Agarwal, A. John, A. Dorfman, R. Grifka, C.A. Figueroa. “Reproducing patient-specific hemodynamics in the Blalock-Taussig circulation using a flexible multi-domain simulation framework: applications for optimal shunt design”. Frontiers in Pediatrics. DOI: 10.3389/fped.2017.00078 pdf_icon_20w.

P. Youssefi, A. Gomez, C.J. Arthurs, R. Sharma, M. Jahangiri, C.A. Figueroa. “Impact of Patient-specific Inflow Velocity Profiles on Haemodynamics of the Thoracic Aorta”. Journal of Biomechanical Engineering. DOI: 10.1115/1.4037857 pdf_icon_20w.

Y.S. Oh, D.E. Berkowitz, R.A. Cohen, C.A. Figueroa, D.G. Harrison, J.D. Humphrey, D.F. Larson, J.A. Leopold, R.P. Mecham, N. Ruiz-Opazo, L. Santhanam, F. Seta, J.Y.J. Shyy, Z. Sun, P.S. Tsao, J. Waggenseil, Z. Galis. “A Special Report on the NHLBI Initiative to Study Cellular and Molecular Mechanisms of Arterial Stiffness and its Association with Hypertension”. Circulation Research. DOI: 10.1161/CIRCRESAHA.117.311703 pdf_icon_20w.

H.W.L. de Beaufort, A. Ferrara, M. Conti, F.L. Moll, J.A. Herwaarden, C.A. Figueroa, J. Bismuth, F. Auricchio, S. Trimarchi. “Comparative Analysis of Porcine and Human Thoracic Aortic Stiffness”. European Journal of Vascular and Endovascular Surgery. DOI: 10.1016/j.ejvs.2017.12.014 pdf_icon_20w.

T.M.J. van Bakel, K.D. Lau, J. Hirsch-Romano, S. Trimarchi, A.L. Dorfman, C.A. Figueroa. “Patient-Specific Modeling of Hemodynamics: Supporting Surgical Planning in a Fontan Circulation Correction”. Journal of Cardiovascular Translational Research. DOI: 10.1007/s12265-017-9781-x pdf_icon_20w.



J.D. Humphrey, D.G. Harrison, C.A. Figueroa, P. Lacolley, S. Laurent. “Central Artery Stiffness in Hypertension and Aging: A Problem with Cause and Consequence.” Circulation Research. Vol 118, pp. 379-381 pdf_icon_20w.

D. Dillon-Murphy, A. Noorani, D.A. Nordsletten, C.A. Figueroa. “Multi-Modality Image-Based Analysis of Hemodynamics of Aortic Dissection”. Biomechanics and Modeling in Mechanobiology. Vol 15, pp. 857-876 pdf_icon_20w.

C.J. Arthurs, K.D. Lau, K. Asrress, S.R. Redwood, C.A. Figueroa. “A Mathematical Model of Coronary Blood Flow Control: Simulation of Patient-Specific Three-Dimensional Haemodynamics during Exercise. American Journal of Physiology – Heart and Circulatory Physiology. DOI:  10.1152/ajpheart.00517.2015 pdf_icon_20w.

F.J.H. Nauta, S. Trimarchi, A.V. Kamman, F.L. Moll, J.A. Herwaarden, H.J. Patel, C.A. Figueroa, K.A. Eagle, J.B. Froehlich. “Update in Management of Type B Aortic Dissection”. Journal of Vascular Medicine. DOI: 10.1177/1358863X16642318 pdf_icon_20w.

J. Alastruey, N. Xiao, H. Fok. T. Schaeffter, C.A. Figueroa. “On the Impact of Modeling Assumptions in Multi-Scale Subject-Specific Models of Aortic Hemodynamics”. Journal of the Royal Society Interface. DOI: 10.1098/rsif.2016.0073 pdf_icon_20w.

S. Ben Ahmed, D. Dillon-Murphy, C.A. Figueroa. “Computational Study of Anatomical Risk Factors in Idealized Models of Type B Aortic Dissection”. European Journal of Vascular and Endovascular Surgery. DOI: 10.1016/j.ejvs.2016.07.025 pdf_icon_20w.

P. Youssefi, A. Gomez, T. He, L. Anderson, N. Bunce, R. Sharma, C.A. Figueroa, M. Jahangiri. “Patient-specific Computational Fluid Dynamics – Assessment of Aortic Hemodynamics in a Spectrum of Aortic Valve Pathologies”. Journal of Thoracic and Cardiovascular Surgery. DOI: 10.1016/j.jtcvs.2016.09.040 pdf_icon_20w.

F.J.H. Nauta, K.D. Lau, C.J. Arthurs, K.A. Eagle, D.M. Williams, S. Trimarchi, H.J. Patel, C.A. Figueroa. “Computational Fluid Dynamics and Aortic Thrombus Formation Following Thoracic Endovascular Aortic Repair”. Annals of Thoracic Surgery. DOI: 10.1016/j.athoracsur.2016.09.067 pdf_icon_20w.

F.J.H. Nauta, A.V. Kamman, E.H. Ibrahim, P.P. Agarwal, B. Yang, K. Kim, D.M. Williams, J.A. Herwaarden, F.L. Moll, K.A. Eagle, S. Trimarchi, H.J. Patel, C.A. Figueroa. “Assessment of CardiOvascular Remodelling following Endovascular aortic repair through imaging and computation: the CORE prospective observational cohort study protocol”. British Medical Journal Open. DOI: 10.1136/bmjopen-2016-012270 pdf_icon_20w.

P. Youssefi, R. Sharma, C.A. Figueroa, M. Jahangiri. “Functional Assessment of Thoracic Aortic Aneurysms – The Future of Risk Prediction?”. British Medical Bulletin. DOI: 10.1093/bmb/ldw049 pdf_icon_20w.

H.W.L. de Beaufort, F.J.H. Nauta, M. Conti, E. Cellitti, C. Trentin, E. Faggiano, G.H.W. van Bogerijen, C.A. Figueroa, F.L. Moll, J.A. Herwaarden, F. Auricchio, S. Trimarchi. “Extensibility and Distensibility of the Thoracic Aorta in Patients with Aneurysm”. Journal of Vascular and Endovascular Surgery. DOI: 10.1016/j.ejvs.2016.11.018 pdf_icon_20w.



K. Lau, C.A. Figueroa. “Simulation of Short-term Pressure Regulation during the Tilt Test in a Coupled 3D-0D Closed-Loop Model of the Circulation.” BMMB. Vol 14, pp. 915-929 pdf_icon_20w.

F. Cuomo, J. Ferruzzi, J.D. Humphrey, C.A. Figueroa. “An experimental-computational study of catheter induced alterations in pulse wave velocity in anesthetized mice.” Ann Biomed Eng. Vol 43(7), pp. 1555-1570 pdf_icon_20w.

M.S. Vieira, T. Hussain, C.A. Figueroa. “Patient-specific Image-based Computational Modeling in Congenital Heart Disease: A Clinician Perspective”. Journal of Cardiology and Therapy. Vol. 2(6), pp. 436-448 pdf_icon_20w.

F. Donati, C.A. Figueroa, N. Smith, P. Lamata, D.A. Nordsletten. “Non-invasive Pressure Difference Estimation from PC-MRI Using the Work Energy Equation”. Medical Image Analysis. Vol 26(1), pp. 159-172pdf_icon_20w.

F.J.H. Nauta, M. Conti, A. Kamman, G. van Bogerijen, J. Tolenaar, F. Auricchio, C.A. Figueroa, J. van Herwaarden, F. Moll, S. Trimarchi. “Biomechanical Changes After Thoracic Endovascular Aortic Repair in Type B Dissection: A Systematic Review”. Journal of Endovascular Therapy. Vol. 22(6), pp. 918-933 pdf_icon_20w.



S. Roccabianca, C.A. Figueroa, G. Tellides, J.D. Humphrey. “Quantification of Regional Differences in Aortic Stiffness in the Aging Human.” J Mech Behav Biomed Mat. Vol. 29, pp. 618-634 pdf_icon_20w.

N. Xiao, J. Alastruey-Arimon, C.A. Figueroa. “A Systematic Comparison Between 1D and 3D Hemodynamics in Compliant Arterial Models.” Int J Num Meth Biomed Eng. Vol. 30(2), pp. 204-231. .

P. Di Achille, G. Tellides, C.A. Figueroa, J.D. Humphrey. “A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms.” Proc Royal Soc A-Math Phys Eng Sci. Volume: 470(2172) pdf_icon_20w.



J.S. Coogan, J.D. Humphrey, C.A. Figueroa. “Computational Simulations of Hemodynamic Changes within Thoracic, Coronary, and Cerebral Arteries Following Early Wall Remodeling in Response to Distal Aortic Coarctation.” BMMB. Vol. 12(1), pp. 79-93 .

P. Moireau, C. Bertoglio, N. Xiao, C.A. Figueroa, C.A. Taylor, D. Chapelle, J.F. Gerbeau. “Sequential Identification of Boundary Support Parameters in a Fluid-Structure Vascular Model using Patient Data.” BMMB. Vol. 12(3), pp. 475-96 .

N. Xiao, J.D. Humphrey, C.A. Figueroa. “Multi-Scale Computational Model of Three-Dimensional Hemodynamics within a Deformable Full-Body Arterial Network.” J Comput Phys. Vol 244, pp. 22-40 .

A. Prasad, N. Xiao, X.Y. Gong, C.K. Zarins, C.A. Figueroa. “A Computational Framework for Investigating the Positional Stability of Aortic Endografts.” BMMB. Vol. 12(5), pp. 869-887 .



P. Moireau, N. Xiao, M. Astorino, C.A. Figueroa, D. Chapelle, C.A. Taylor, J.F. Gerbeau. “External Tissue Support and Fluid-Structure Simulation in Blood Flows.” BMMB. Vol. 11(1), pp. 1-18 .



E.O. Kung, A.S. Les, C.A. Figueroa, F. Medina, R.B.Wicker, M.V. McConnell, C.A. Taylor. “In Vitro Validation of Finite Element Analysis of Blood Flow in Deformable Models.” Ann Biomed Eng. Vol. 39(7), pp. 1947-1960.

A. Prasad, L.K. To, M.L. Gorrepati, C.K. Zarins, C.A. Figueroa. “Computational Analysis of Stresses Acting on Inter-modular Junctions in Thoracic Aortic Endografts.” J Endovas Ther. Vol. 18, pp. 559-568 .

J.F. LaDisa, R.J. Dholakia, C.A. Figueroa, I.E. Vignon-Clementel, F.P. Chan, M.M. Samyn, J.R. Cava, C.A. Taylor, J.A. Feinstein. “Computational Simulations Demonstrate Altered Wall Shear Stress in Aortic Coarctation Patients Previously Treated by Resection with End-to-End Anastomosis.” Congen Heart Disea. Vol. 6, pp. 432-443 .

R. Raghu, I.E. Vignon-Clementel, C.A. Figueroa, C.A. Taylor. “Comparative Study of Viscoleastic Arterial Wall Models in Nonlinear One-dimensional Finite Element Simulations of Blood Flow.” J Biomech Eng. Vol. 133(8), pp. 081003-1:11.

J.F. LaDisa*, C.A. Figueroa*, I.E. Vignon-Clementel, H.J. Kim, N. Xiao, L.M. Ellwein, F.P. Chan, J.A. Feinstein, C.A. Taylor. “Computational Simulations for Aortic Coarctation: Representative Results from a Sampling of Patients.” J Biomech Eng. Vol. 133(9), pp. 091009-1:9..



I.E. Vignon-Clementel, C.A. Figueroa, K.E. Jansen, C.A. Taylor. “Outflow Boundary Conditions for Three-Dimensional Simulations of Non-Periodic Blood Flow and Pressure Fields in Deformable Arteries.” Comp Meth Biomech Biomed Eng. Vol. 13(5), pp. 625-640 .

A.S. Les, S.C. Shadden, C.A. Figueroa, J.M. Park, M.M. Tedesco, R.J. Herfkens, R.L. Dalman, C.A. Taylor. “Quantification of Hemodynamics in Abdominal Aortic Aneurysms During Rest and During Exercise Using Magnetic Resonance Imaging and Computational Fluid Dynamics.” Ann Biomed Eng. Vol. 38 (4), pp. 1288-1313 .

C.A. Figueroa, C.A. Taylor, V. Yeh, A.J. Chiou, M.L. Gorrepati, C.K. Zarins. “Preliminary 3D Computational Analysis of the Relationship between Aortic Displacement Force and Direction of Endograft Movement.” J Vasc Surg. Vol. 51 (6), pp. 1488-1497.

M. Zhou, O. Sahni, H.J. Kim, C.A. Figueroa, C.A. Taylor, M.S. Shephard, K.E. Jansen. “Cardiovascular Flow Simulation at Extreme Scale.” Computat Mech. Vol. 46, pp. 71-82 .

H.J. Kim, I.E. Vignon-Clementel, C.A. Figueroa, K.E. Jansen, C.A. Taylor. “Developing Computational Methods for Three-Dimensional Finite Element Simulations of Coronary Blood Flow.” Fin Elem Anal Design Vol. 46, pp. 514-525 .

H.J. Kim, I.E. Vignon-Clementel, J.S. Coogan, C.A. Figueroa, K.E. Jansen, C.A. Taylor. “Patient-specific Modeling of Blood Flow and Pressure in Human Coronary Arteries.” Ann BiomeD Eng. Vol. 38(10), pp. 3195-3209

G. Xiong, C.A. Figueroa, N. Xiao, C.A. Taylor. “Simulation of Blood Flow in Deformable Vessels Using Subject-specific Geometry and Assigned Variable Mechanical Wall Properties.” Inter J Num Meth Biomed Eng Vol. 27(7), pp. 1000–1016 .



C.A. Figueroa*, S. Baek*, C.A. Taylor, J.D. Humphrey. “A Computational Framework for Coupled Fluid-Solid Growth in Cardiovascular Simulations.” Comp Meth Appl Mech Eng. Vol. 198, pp. 3583-3602.

H.J. Kim, C.A. Figueroa, T.J.R. Hughes, K.E. Jansen, C.A. Taylor. “Augmented Lagrangian Method for Constraining the Shape of Velocity Profiles at Outlet Boundaries for Three-dimensional Finite Element Simulations of Blood Flow.” Comp Meth Appl Mech Eng. Vol. 198, pp. 3551-3566.

C.A. Figueroa, C.A. Taylor, V. Yeh, A.J. Chiou, C.K. Zarins. “Effect of Curvature on Displacement Forces Acting on Aortic Endografts: a three dimensional computational analysis.” J Endovas Ther. Vol. 16, pp. 284-294.

C.A. Figueroa, C.A. Taylor, A.J. Chiou, V. Yeh, C.K. Zarins. “Magnitude and Direction of Pulsatile Displacement Forces Acting on Thoracic Aortic Endografts.” J Endovas Ther. Vol. 16, pp. 350-358.

H.J. Kim, I.E. Vignon-Clementel, C.A. Figueroa, J.F. LaDisa, K.E. Jansen, J.A. Feinstein, C.A. Taylor. “On Coupling a Lumped Parameter Heart Model and a Three-Dimensional Finite Element Aorta Model.” Ann Biomed Eng. Vol. 37 (11), pp. 2153-2169 .

C.A. Taylor, C.A. Figueroa. “Patient-specific Modeling of Cardiovascular Mechanics.” Ann Rev Biomed Eng. Vol. 11, pp. 109-134.



C.A. Figueroa, I.E. Vignon-Clementel, K.C. Jansen, T.J.R. Hughes, C.A. Taylor. “A Coupled Momentum Method for Modeling Blow Flow in Three-Dimensional Deformable Arteries.” Comp Meth Appl Mech Eng. Vol. 195, Issues 41-43, pp. 5685-5706.

I.E. Vignon-Clementel, C.A. Figueroa, K.E. Jansen, C.A. Taylor. “Outflow Boundary Conditions for Three-dimensional Finite Element Modeling of Blood Flow and Pressure in Arteries.” Comp Meth Appl Mech Eng. Vol. 195, pp. 3776-3796.