Kevin D. Lau

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Research Interests

  • 3D and 1D methods for fluid-structure simulation of blood flow
  • Reduced order boundary conditions for blood flow modelling
  • Physiological autoregulation of blood flow
  • 3D methods for simulation of mitral valve surgery
  • Finite element methods for biofluids and biomechanics
  • Discrete element methods for haemodynamic delivery of magnetic particles

 

Biography

After completing my Masters in Aeronautical Engineering (MEng) from Imperial College London in 2006, I developed an interest in the role of fluid and solid mechanics in answering biological questions. Joining the Centre for Mathematics and Physics in the Life Sciences and EXperimental Biology (CoMPLEX) Doctoral Training Centre at University College London in 2007, I completed a Masters in Research (MRes) in 2008 and in combination with the Department of Mechanical Engineering, a Doctor of Philosophy (PhD) in Numerical Simulation of Mitral Valve Function in 2011. Interested in developing research tools to address key clinical and physiological questions, I joined the Figueroa Lab in the Department of Biomedical Engineering at King’s College London in July 2012. Here my work is focused upon the development of numerical boundary conditions that represent key physiological autoregulatory feedback mechanisms. Integrated in a parallelised, fluid-structure interaction, blood flow solver, these tools will enable both bioengineers and clinicians to better understand the role that biomechanics in both healthy and diseased conditions.  

Journal Papers

2011

  • K. D. Lau, V. Díaz, P. Scambler, G. Burriesci. “Fluid-structure interaction study of the edge-to-edge repair technique on the mitral valve.” J Biomech, 44:2409–2417, Jul 2011. pdf_icon_20w

 

  • J. Riegler, K. D. Lau, A. Garcia-Prieto, A. N. Price, T. Richards, Q. A. Pankhurst, M. F. Lythgoe. “Magnetic cell delivery for peripheral arterial disease: A theoretical framework.” Med Phys, 38(7):3932–3943, Jul 2011. pdf_icon_20w

2010

  • K. D. Lau, V. Díaz, P. Scambler, G. Burriesci. “Mitral valve dynamics in structural and fluid structure interaction models.” Medical Engineering & Physics, 32(9):1057–1064, Nov 2010. pdf_icon_20w

 

PhD Thesis

  • Numerical Simulation of Mitral Valve Function.” University College London, London, UK. March 2012. pdf_icon_20w