Pulsatile aortic blood flow and pressure exert time-varying loads on all intra-aortic devices. Long-term durability of these devices requires continuous mechanical fixation of the vascular prosthesis to prevent displacement. Failure of fixation can lead to device migration and adverse clinical events, such as secondary interventions, endoleaks, rupture and death. In humans, aortoiliac geometry is usually curved, with anterior angulation of the aneurysmal aorta and posterior curvature of the iliac arteries in the pelvis. This results in significant centerline lumen curvature of the aortoiliac segment and significant post-implantation curvature of implanted aortic endografts. In cases of severe aneurysm and aortic neck angulation, this curvature may be quite pronounced and may become more accentuated over time due to endograft migration. In this study, we investigated the impact of curvature on the displacement forces experienced by aortic endografts using computational fluid dynamics techniques.
- “Preliminary 3D Computational Analysis of the Relationship between Aortic Displacement Force and Direction of Endograft Movement.” Journal of Vascular Surgery Vol. 51 (6), pp. 1488-1497.
- “Effect of Curvature on Displacement Forces Acting on Aortic Endografts: a three dimensional computational analysis.” Journal of Endovascular Therapy Vol. 16, pp. 284-294.